Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CYCLESSA | Aspen Global | N-021090 RX | 2000-12-20 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
LYNORAL | Organon | N-005490 DISCN | 1982-01-01 | 2 products |
FEMINONE | Pharmacia & Upjohn | N-016649 DISCN | 1982-01-01 | 1 products |
ESTINYL | Merck & Co | N-005292 DISCN | 1982-01-01 | 3 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
DEMULEN 1/50-21 | G.D. Searle | N-016927 DISCN | 1982-01-01 | 1 products |
DEMULEN 1/50-28 | G.D. Searle | N-016936 DISCN | 1982-01-01 | 1 products |
DEMULEN 1/35-28 | G.D. Searle | N-018160 DISCN | 1982-01-01 | 1 products |
DEMULEN 1/35-21 | G.D. Searle | N-018168 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
TWIRLA | Agile Therapeutics | N-204017 RX | 2020-02-14 | 1 products, RLD, RS |
BALCOLTRA | Avion Pharmaceuticals | N-208612 RX | 2018-01-09 | 1 products, RLD, RS |
TYBLUME | Exeltis | N-209405 RX | 2020-03-30 | 1 products, RLD, RS |
SEASONALE | Teva | N-021544 RX | 2003-09-05 | 1 products, RLD, RS |
SEASONIQUE | Teva | N-021840 RX | 2006-05-25 | 1 products, RLD, RS |
LOSEASONIQUE | Teva | N-022262 RX | 2008-10-24 | 1 products |
QUARTETTE | Teva | N-204061 RX | 2013-03-28 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ORTHO EVRA | Johnson & Johnson | N-021180 DISCN | 2001-11-20 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
NORETHINDRONE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE | Allergan | N-022573 RX | 2010-12-22 | 1 products, RLD, RS |
TRI-NORINYL 28-DAY | Dr Reddys Laboratories | N-018977 RX | 1984-04-13 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ORTHO CYCLEN-21 | Johnson & Johnson | N-019653 DISCN | 1989-12-29 | 1 products |
ORTHO CYCLEN-28 | Johnson & Johnson | N-019653 DISCN | 1989-12-29 | 1 products, RLD |
ORTHO TRI-CYCLEN | Johnson & Johnson | N-019697 DISCN | 1992-07-03 | 2 products |
ORTHO TRI-CYCLEN LO | Johnson & Johnson | N-021241 DISCN | 2002-08-22 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
LO/OVRAL | Cadence Pharmaceuticals | N-017612 DISCN | 1982-01-01 | 1 products, RLD |
OVRAL | WYETH PHARMS | N-016672 DISCN | 1982-01-01 | 1 products |
OVRAL-28 | WYETH PHARMS | N-016806 DISCN | 1982-01-01 | 1 products |
LO/OVRAL-28 | WYETH PHARMS | N-017802 DISCN | 1982-01-01 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ANNOVERA | Mayne Group | N-209627 RX | 2018-08-10 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
affodel | ANDA | 2022-09-20 |
afirmelle | ANDA | 2021-02-17 |
altavera | ANDA | 2022-03-01 |
alyacen 1/35 | ANDA | 2023-06-07 |
alyacen 1/35 alyacen 7/7/7 | ANDA | 2017-09-08 |
alyacen 7/7/7 | ANDA | 2021-03-18 |
amabelz | ANDA | 2024-01-10 |
amethia | ANDA | 2022-08-16 |
amethyst | ANDA | 2022-01-31 |
annovera | New Drug Application | 2022-08-23 |
Expiration | Code | ||
---|---|---|---|
ETHINYL ESTRADIOL / SEGESTERONE ACETATE, ANNOVERA, MAYNE PHARMA | |||
2023-08-10 | NCE | ||
ETHINYL ESTRADIOL / LEVONORGESTREL, TYBLUME, EXELTIS USA INC | |||
2023-03-30 | NDF | ||
ETHINYL ESTRADIOL / LEVONORGESTREL, TWIRLA, AGILE | |||
2023-02-14 | NP |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Ethinyl Estradiol / Segesterone Acetate, Annovera, Mayne Pharma | |||
10918649 | 2039-06-21 | DP | |
10925882 | 2039-06-21 | DP | |
10940157 | 2039-06-21 | DP | |
11529308 | 2039-06-21 | DP | |
10632066 | 2039-02-01 | U-2786, U-2787 | |
10765628 | 2039-02-01 | U-2786, U-2787 | |
10780047 | 2039-02-01 | U-2786, U-2787 | |
Drospirenone / Ethinyl Estradiol / Levomefolate Calcium, Beyaz, Bayer Hlthcare | |||
11617751 | 2030-07-17 | DP | U-1, U-3572, U-3573, U-3574 |
8617597 | 2030-02-08 | DP | |
Ethinyl Estradiol / Levonorgestrel, Quartette, Teva Branded Pharm | |||
8415332 | 2029-03-11 | DP | |
8450299 | 2025-10-07 | U-1 | |
Ethinyl Estradiol / Norethindrone Acetate, Lo Loestrin Fe, Apil | |||
7704984 | 2029-02-02 | U-1, U-1090 | |
Ethinyl Estradiol / Levonorgestrel, Loseasonique, Teva Branded Pharm | |||
7855190 | 2028-12-05 | U-1 | |
7858605 | 2023-06-23 | DP | |
7615545 | 2023-06-15 | U-1 | |
Ethinyl Estradiol / Levonorgestrel, Twirla, Agile | |||
8246978 | 2028-08-26 | DP | |
8747888 | 2028-07-10 | DP | |
9050348 | 2028-07-10 | DP | |
Ethinyl Estradiol / Levonorgestrel, Balcoltra, Avion Pharms | |||
7838042 | 2027-06-01 | DP | U-3251 |
Ethinyl Estradiol / Levonorgestrel, Seasonique, Teva Branded Pharm | |||
7320969 | 2024-01-30 | U-828 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 202 | 1 | 6 | 5 | 4 | 218 |
Contraception | D003267 | — | — | 18 | 16 | 47 | 20 | 28 | 127 |
Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | 3 | 2 | 6 | 10 | 10 | 31 |
Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 5 | 12 | 7 | 1 | 3 | 24 |
Pulmonary tuberculosis | D014397 | EFO_1000049 | A15 | — | 14 | 11 | 1 | 2 | 23 |
Dysmenorrhea | D004412 | HP_0100607 | N94.6 | 1 | 4 | 11 | 3 | 4 | 20 |
Cataract | D002386 | HP_0000518 | H26.9 | 1 | 1 | 1 | 12 | 2 | 17 |
Hiv infections | D015658 | EFO_0000764 | B20 | 7 | 2 | — | 1 | 5 | 15 |
Multidrug-resistant tuberculosis | D018088 | EFO_0007381 | — | — | 7 | 8 | 3 | 3 | 15 |
Infections | D007239 | EFO_0000544 | — | 8 | 1 | 3 | 1 | 2 | 15 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hepatitis c | D006526 | — | B19.2 | 6 | — | 1 | — | 1 | 8 |
Metrorrhagia | D008796 | HP_0100608 | N92.1 | — | 3 | 1 | — | 2 | 6 |
Keratitis | D007634 | HP_0000491 | H16 | — | 1 | 5 | — | — | 5 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 1 | 3 | — | — | 5 |
Keratoconus | D007640 | EFO_0004223 | H18.6 | 1 | 1 | 1 | — | 3 | 5 |
Community-acquired infections | D017714 | — | — | — | 2 | 3 | — | — | 5 |
Lung diseases | D008171 | HP_0002088 | J98.4 | 2 | 1 | 2 | — | — | 4 |
Female infertility | D007247 | EFO_0008560 | N97 | 2 | 1 | 1 | — | 1 | 4 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 3 | — | 1 | — | — | 4 |
Extensively drug-resistant tuberculosis | D054908 | — | — | — | 4 | 4 | — | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pharmacokinetics | D010599 | — | — | 18 | 1 | — | — | 2 | 21 |
Neoplasms | D009369 | — | C80 | 5 | 1 | — | — | 1 | 7 |
Parkinson disease | D010300 | EFO_0002508 | G20 | 3 | 1 | — | — | — | 4 |
Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | 1 | — | — | — | 2 |
Hemostasis | D006487 | — | — | — | 2 | — | — | — | 2 |
Pregnancy | D011247 | EFO_0002950 | Z33.1 | 1 | 1 | — | — | — | 2 |
Depression | D003863 | — | F33.9 | — | 1 | — | — | 1 | 2 |
Bipolar disorder | D001714 | EFO_0000289 | F30.9 | 1 | 1 | — | — | — | 2 |
Gonadal dysgenesis | D006059 | — | — | — | 2 | — | — | — | 2 |
Cholangitis | D002761 | HP_0030151 | K83.0 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 12 | — | — | — | 1 | 13 |
Therapeutic equivalency | D013810 | — | — | 11 | — | — | — | 1 | 12 |
Schizophrenia | D012559 | EFO_0000692 | F20 | 5 | — | — | — | — | 5 |
Drug interactions | D004347 | — | — | 5 | — | — | — | — | 5 |
Heart failure | D006333 | HP_0001635 | I50 | 2 | — | — | — | 3 | 5 |
Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 2 | — | — | — | 2 | 4 |
Cystic fibrosis | D003550 | EFO_0000390 | E84 | 4 | — | — | — | — | 4 |
Asthma | D001249 | EFO_0000270 | J45 | 4 | — | — | — | — | 4 |
Benign familial pemphigus | D016506 | — | Q82.8 | 1 | — | — | — | 3 | 4 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | 4 | — | — | — | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pathologic dilatation | D004108 | — | — | — | — | — | — | 3 | 3 |
Regeneration | D012038 | — | — | — | — | — | — | 3 | 3 |
Retinal detachment | D012163 | EFO_0005773 | H33.2 | — | — | — | — | 2 | 2 |
Macular degeneration | D008268 | EFO_0001365 | H35.30 | — | — | — | — | 2 | 2 |
Venous thrombosis | D020246 | HP_0004936 | I82.40 | — | — | — | — | 2 | 2 |
Peritonitis | D010538 | EFO_0008588 | K65 | — | — | — | — | 2 | 2 |
Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 2 | 2 |
Gingivitis | D005891 | HP_0000230 | K05.10 | — | — | — | — | 2 | 2 |
Pneumococcal pneumonia | D011018 | EFO_1001474 | J13 | — | — | — | — | 1 | 1 |
Pneumococcal infections | D011008 | EFO_0000772 | J13 | — | — | — | — | 1 | 1 |
Drug common name | Ethinyl estradiol |
INN | ethinylestradiol |
Description | 17alpha-ethynylestradiol is a 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration. It has a role as a xenoestrogen. It is a 17-hydroxy steroid, a terminal acetylenic compound and a 3-hydroxy steroid. It is functionally related to a 17beta-estradiol and an estradiol. |
Classification | Small molecule |
Drug class | estrogens |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C |
PDB | — |
CAS-ID | 57-63-6 |
RxCUI | — |
ChEMBL ID | CHEMBL691 |
ChEBI ID | 4903 |
PubChem CID | 5991 |
DrugBank | DB00977 |
UNII ID | 423D2T571U (ChemIDplus, GSRS) |